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Uncontrolled Asthma with Hypereosinophilia

Year: 2025
Type: article
Abstract: Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare inflammatory disease characterized by asthma, necrotizing vasculitis, extravascular granulomas, and blood and tissue eosinophilia. EGPA progresses through prodromic, eosinophilic, and vasculitic phases. These phases often overlap and sometimes do not progress in the expected sequence. A diagnosis of EGPA should be considered in patients who present with asthma, chronic rhinosinusitis, and eosinophilia, especially when evidence of end-organ involvement such as peripheral neuropathy, lung infiltrates, cardiomyopathy, or issues affecting the skin, gastrointestinal tract, or kidneys is present.
Author: Mi-Ae Kim
Language: English
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4413000256
FWCI:
Cites: 8
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Related to: 10