Quantifying localized heatwave impact on mortality: a multi-country modeling study in the Asia–Pacific region
Year: 2025
Type: article
Study design: Observational Study
Abstract: Background: Heatwave is a global health threat. However, existing heatwave definitions often rely on fixed temperature thresholds without incorporating region-specific health outcomes or population acclimatization, limiting their applicability across diverse climatic and demographic contexts. We aimed to assess the impact of localized heatwave on mortality based on a proposed framework of health-based heatwave definition. Methods: Based on daily data on death and weather from 25 cities in Australia, China, South Korea, and Thailand, we proposed a health-based excess heat factor (HEHF) to define the localized heatwave. First, a tiered health risk-based (THR) approach was used to fit the heatwave-mortality association to detect the region-specific temperature threshold for heatwave. Then, the HEHF was derived from a three-day-averaged temperature exceeding the region-specific heatwave threshold multiplied by the acclimatization index, reflecting the difference between recent (past three-day) and preceding (past thirty-day) average temperatures. Finally, the mortality burden attributable to heatwaves was estimated to compare the performance of distinct heatwave definitions including the HEHF, percentile-based definition, and country-specific official definition. Findings: A total of 2,255,634 deaths from four countries were analyzed. Heatwave of all definitions was associated with an increased mortality risk in four countries, with a higher risk estimated by HEHF. The HEHF not only detected a health-based, localized, and time-varying temperature threshold for the heatwave but also captured a continuous pattern of mortality risk associated with changes in heatwave intensity. Compared with percentile-based and country-specific official definitions, using the HEHF also yielded a larger proportion of deaths attributable to heatwaves, accounting for 8.68% (95% CI: 7.19%, 10.50%) in China, 4.50% (95% CI: 3.33%, 5.58%) in Thailand, 2.99% (95% CI: 1.54%, 4.33%) in Australia, and 1.98% (95% CI: 1.24%, 2.71%) in South Korea. The subtropical zone exhibited a higher attributable fraction than temperate and tropical zones. Interpretation: This multi-country study has developed a generalizable and health-based framework for defining the localized heatwave, assisting in assessing and comparing health impact of heatwaves across regions and climates. Funding: National Natural Science Foundation of China.
Institutions: Anhui Medical University, Griffith University, City University of Hong Kong, Jiangsu Provincial Center for Disease Control and Prevention, Anhui Provincial Center for Disease Control and Prevention, Queensland University of Technology, Chinese Center For Disease Control and Prevention, Seoul National University, International Centre for Diarrhoeal Disease Research, Tsinghua University, First Affiliated Hospital of Anhui Medical University
Language: English
Subfield: Health, Toxicology and Mutagenesis
Field: Environmental Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $4,250
OpenAlex ID: W4413034786
