Work

Percutaneous Pulmonary Artery Mechanical Thrombectomy for the Treatment of Patients With Acute Pulmonary Embolism

Year: 2025

Type: article

Abstract: Background: Percutaneous pulmonary artery mechanical thrombectomy (MT) has great potential as a reperfusion treatment strategy for acute pulmonary embolism (APE). Aim: To evaluate the efficacy and safety of percutaneous MT for the treatment of APE. Method: Continuous MT is performed on patients with acute massive area or submassive area pulmonary embolism using a thrombus aspiration catheter. The main efficacy indicators are the improvement of respiratory and circulatory functions, including blood oxygen saturation, troponin, and N‐BNP, 48 h after blood clot aspiration and resection surgery. The secondary efficacy indicators are postoperative clinical stability and discharge survival rate. The safety indicators are surgical complications and major bleeding events. Result: This study included 30 patients with APE. After undergoing MT, 29 patients achieved clinical stability and were discharged smoothly, with a discharge survival rate of 96.7%. One patient died due to direct respiratory and cardiac arrest caused by APE despite rescue efforts. A total of 29 patients showed a 17.0% increase in arterial oxygen saturation 48 h after surgery; the gap has statistical significance ( p < 0.05). Comparison of cardiac function‐related indicators showed a decrease of 0.099 in cardiac troponin after surgery and 7024.7 in NT proBNP after surgery, with statistically significant differences ( p < 0.05). Three patients experienced hemoptysis during percutaneous pulmonary artery thrombectomy, and two patients stopped hemoptysis within half an hour. Another patient underwent transcatheter bronchial artery embolization during the same period. Two APE patients developed inferior vena cava (under the filter) thromboembolism at 15 and 60 days after thrombectomy and accepted percutaneous inferior vena cava thrombectomy. Conclusion: Percutaneous pulmonary artery MT has great benefits in relieving pulmonary artery obstruction and improving respiratory and circulatory function while also having good safety. We recommend early use of MT in patients with acute massive area pulmonary embolism.

Source: Journal of Cardiac Surgery

DOI: 10.1155/jocs/7604402

Authors: Li-ping Jiang, Qi-bin Wang, Xu Wang, Weiwei Niu, Yan Liu

Institutions: Shihezi University, First Affiliated Hospital of Shihezi University Medical College

Language: English

Topic: Venous Thromboembolism Diagnosis and Management

Subfield: Internal Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,700