Frequency of Steroid Induced Diabetes in Young Patients Treated Pre B-Cell Acute Lymphoblastic Leukemia
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: It has been noted in the literature that while there is information on the prevalence of steroid-induced diabetes, there is little information on its severity or rate. There is no proof for the local populace either. Therefore, the goal of this research is to ascertain if the level of concern is high or low among local community members who have pre-B-cell acute lymphoblastic leukemia. Materials & Methods: Total 100 patients between the ages of 18 and 50, both male and female, who were diagnosed with pre-B-cell acute lymphoblastic leukemia and who were receiving oral or intravenous steroids of any kind for a minimum of months were included. We excluded patients with unstable glucose levels due to another known co-morbidity and chronic diabetes. Steroid-induced diabetes is defined as blood glucose levels that are randomly higher than or equal to 200 mg/dl on two separate occasions after starting steroidal medication for more than three months. Patients with diabetes brought on by steroids were treated according to conventional procedure. Results: The study's participants ranged in age from 18 to 50, with a mean age of 31.11 ± 6.51 years. Seventy-eight (78.0%) of the patients were between the ages of 18 and 35. With a male to female ratio of 1.4:1, 58 (58.0%) of the 100 patients were men and 42 (42.0%) were women. In our study, 40 (40.0%) of the young patients receiving treatment for pre-B-cell acute lymphoblastic leukemia also developed hyperglycemia brought on by steroids. Conclusion: Our research revealed a relatively high incidence of steroid-induced diabetes in young children receiving treatment for pre-B-cell acute lymphoblastic leukemia.
Authors: Maleeha Ayub, Iqra Hameed, Ahmed Imran Siddiqi, Muhammad Haris Naveed
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W4413039444