Work

Context is everything: The role of polo-like kinase I during C. elegans oocyte meiosis

Year: 2025

Type: article

Abstract: Meiotic chromosome segregation in oocytes often relies on meiosis-specific modifications of mitotic molecular mechanisms to respond to the unique challenges of this asymmetric division. In this issue, Narula and Wignall (https://doi.org/10.1083/jcb.202503080) demonstrate how the conserved polo-like kinase in Caenorhabditiselegans, PLK-1, has been repurposed in unexpected ways to ensure accurate meiotic chromosome segregation during oogenesis.

Source: The Journal of Cell Biology

DOI: 10.1083/jcb.202506208

Author: Needhi Bhalla

Institution: University of California, Santa Cruz

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: bronze

Funders: National Institutes of Health, National Institute of General Medical Sciences

Awards: G274890019, G9000019603