Year: 2025
Type: article
Abstract: Calcific aortic valve disease (CAVD) is a progressive remodeling of the aortic valve leaflets which include thickening, fibrosis, and mineralization, evolving from atherosclerosis to aortic sclerosis and calcific aortic stenosis.Age is an important and non-modifiable risk factor for CAVD, along with dyslipidemia, hypertension, plasma lipoprotein(a) levels, obesity, and diabetes mellitus, which are modifiable factors.The assessing of calcific aortic valve is extremely important, especially, because CAVD is a progressive condition that can lead to aortic stenosis; it has serious clinical consequences if left untreated.The long-term outcomes of patients with aortic sclerosis and mild aortic stenosis detected at the time of clinically indicated echocardiography are important.Patients with aortic sclerosis are >25 times more likely to require aortic valve intervention than those with no CAVD, and follow-up echocardiography should be considered within 3-4 years in those with mild aortic stenosis [1].Appropriate assessment of CAVD is very important equally, for patient diagnostic and follow-up, but also for treatment and prognosis.The recently published meta-analysis of Huang et al. [2] concluded that the ultrasound demonstrates high accuracy in diagnosing senile CAVD; however, misdiagnosis or missed diagnosis can happened because echocardiography, even it is the golden standard imaging modality, it does not completely eliminate this possibility.Therefore, even echocardiography is considered the gold standard imaging modality for assessing CAVD it has some strengths and challenges.The appropriate assessing of CAVD is crucial for early diagnosis, risk assessment, monitoring progression, and deciding on
Source: Echocardiography
DOI: 10.1111/echo.70261
Language: English
Subfield: Cardiology and Cardiovascular Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $3,700
OpenAlex ID: W4413055533