Practical examples of biocatalysis in industry
Year: 2025
Type: article
Abstract: Biocatalysis has been used in industrial settings, especially in the pharmaceutical industry, for decades. In this review, we showcase the six most prominent enzyme classes in industrial biocatalysis: keto-reductases, ene-reductases, imine-reductases, transaminases, oxygenases, and hydrolases. For each class, several examples are presented that highlight the substrate scope and enantioselectivity of these biotransformations from milligram to multikilogram scale.
Source: Comptes Rendus Chimie
DOI: 10.5802/crchim.408
Authors: Amelia K. Gilio, Miguel A. Abdo, Carlos A. Martinez, Andrew T. Palaia, Jovan Livada
Institution: Pfizer (United States)
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413060613