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5-Amino-1,2,4-triazole-3-carboxamide homologues and their biological potential

Year: 2025

Type: article

Abstract: New homologues of 5-amino-1,2,4-triazole-3-carboxamide, viz., 5-(ω-aminoalkyl)-1,2,4-triazole-3-carboxamides have been synthesized. The intermediate acyloxalamidrazones undergo thermal cyclization to 1,2,4-triazoles with the better yield in the absence of catalyst while in the presence of 10 mol

Source: Mendeleev Communications

DOI: 10.71267/mencom.7753

Authors: Eugenia S Oleynik, Anna A Shmarina, Ekaterina R Mitina, Ekaterina A Mikhina, Ilya A Semenov, Ekaterina D Savina, Lyubov E Grebenkina, Ekaterina M Zhidkova, Ekaterina A Lesovaya, Elizaveta N Vetrova, Olga N Sineva, Andrey Valerievich Matveev

Institutions: MIREA - Russian Technological University, Russian Cancer Research Center NN Blokhin, Peoples' Friendship University of Russia, Ryazan State Medical University named after Academician I.P. Pavlov, Gamalei Institute of Epidemiology and Microbiology, Gause Institute of New Antibiotics Russian Academy of Medical Sciences

Language: English

Topic: Structural and Chemical Analysis of Organic and Inorganic Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

Funders: MIREA - Russian Technological University, Russian Science Foundation, Ministry of Science and Higher Education of the Russian Federation

Award: G4090599177

OpenAlex ID: W4413064756

FWCI: 0.292

Cites: 17

Cited by: 1

Related to: 10