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Unveiling an underestimated potential of vanillin-derived alkynes: synthesis of highly functionalized 3(2H)-furanone with antiradical activity

Year: 2025

Type: article

Abstract: Target-oriented synthesis of highly functionalized 3(2H)-furanone from vanillin through several alkyne intermediates was realized in six steps. The title compound bearing two 4-hydroxy-3-methoxyphenyl moieties showed antiradical activity 1.54 times higher compared to Trolox.

Source: Mendeleev Communications

DOI: 10.71267/mencom.7727

Authors: Olesya V Shabalina, Dmitrii Andreevich Shabalin

Institutions: Irkutsk State University, A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: bronze

OpenAlex ID: W4413065005

FWCI:

Cites: 22

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Related to: 10