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Chemoradiotherapy for recurrent CBTs case report

Year: 2025
Type: article
Study design: Case Report
Abstract: BACKGROUND: Carotid body tumors (CBTs) are rare paragangliomas with an incidence of 1-2 per 100,000 individuals. While surgical resection remains the standard treatment, postoperative recurrence poses a clinical challenge. CASE PRESENTATION: We describe a 49-year-old female with recurrent CBT involving the jugular foramen, managed with IGRT (60 Gy/30 fractions) and 4 cycles of CVD chemotherapy. Post-treatment RECIST evaluation revealed stable disease, supporting chemoradiotherapy as a salvage option for anatomically complex recurrences. CONCLUSION: This case underscores the necessity for standardized protocols and further research to validate multimodal therapy in recurrent CBTs.
Authors: Guangyu Liu, Shuangyan Zhao, Jiankai Wang, Xiaoyu Duan, Hongyi Cai
Language: English
Subfield: Surgery
Field: Medicine
Open Access status: gold
Estimated APC paid: $1,690
OpenAlex ID: W4413101042
FWCI: 0.892
Cites: 18
Cited by: 1
Related to: 10