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Acute Localized Exanthematous Pustulosis After Face and Neck Rhytidectomy: A Case of Locus Minoris Resistentiae

Year: 2025

Type: article

Abstract: We report a case of a 52-year-old woman who developed acute localized exanthematous pustulosis, a rare drug reaction, after cefazolin administration for a face and neck surgery. The rash was confined to the surgical areas, suggesting a locus minoris resistentiae, a phenomenon where a site of previous injury becomes more vulnerable to a subsequent insult. The rash resolved with corticosteroids. We review the clinical features, causes, and management of acute localized exanthematous pustulosis.

Source: Plastic & Reconstructive Surgery Global Open

DOI: 10.1097/gox.0000000000007052

Authors: Liliana Fort, Lucia Seminario-Vidal, Amber N. Pepper, Alicia Billington

Institution: University of South Florida

Language: English

Topic: Drug-Induced Adverse Reactions

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,195