Work

Zero-Field Overhauser Dynamic Nuclear Polarization

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Overhauser dynamic nuclear polarization (O–DNP) enables the production of hyperpolarization in liquids via the dissolution of nitroxide radicals. However, the application of magnetic fields has been inevitable. In the present study, we experimentally demonstrate that water can be hyperpolarized through O–DNP at effectively zero magnetic field. Selective saturation induced by circularly polarized RF fields, generated by two orthogonal RF coils, effectively circumvents the concurrence of positive and negative polarizations that would otherwise significantly deteriorate O–DNP efficiency. Through electron-to-nuclear spectral mapping, the electron paramagnetic resonance spectrum of the nitroxide radical was recorded at a magnetic field of 2 nT. A direct comparison revealed that O–DNP with circularly polarized RF is more than 10 3 times as efficient as that with linearly polarized RF. Finally, at a near-zero field, Overhauser-enhanced 1 H nuclear magnetic resonance from water was observed without the need for auxiliary aids such as sample shuttling or field cycling.

Source: ACS Omega

DOI: 10.1021/acsomega.5c03912

Authors: Seong-Joo Lee, Kwon Kyu Yu, Seong-min Hwang, Nam-Woong Song, Kiwoong Kim, Jeong Hyun Shim

Institutions: Korea Research Institute of Standards and Science, Chungbuk National University, Korea University of Science and Technology

Language: English

Topic: Advanced NMR Techniques and Applications

Subfield: Spectroscopy

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,935

Funders: Korea Research Institute of Standards and Science, Institute for Information and Communications Technology Promotion