Year: 2025
Type: article
Abstract: Alcohols are highly common organic compounds but remain scarce as alkyl donors in synthetic procedures. Here, we describe an electrochemical procedure for their deoxygenative cross-electrophile coupling with hydrosilanes, furnishing organosilane products in good to excellent yields. Mechanistic studies provide insights into the operating pathways of this semi-paired electrolytic transformation, suggesting that silyl ethers are likely reaction intermediates. Furthermore, a unified mechanistic proposal is presented that accounts for observed reactivity differences with analogous deoxygenative electrocarboxylation.
Institution: KTH Royal Institute of Technology
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: hybrid
Estimated APC paid: $5,510
Funders: National Science Foundation, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Stiftelsen för Strategisk Forskning, National Science Council, Stiftelsen Olle Engkvist Byggmästare, Vetenskapsrådet, China Scholarship Council, Stiftelsen för Strategisk Forskning, European Research Council, National Supercomputing Center, Korea Institute of Science and Technology Information, HORIZON EUROPE European Research Council
OpenAlex ID: W4413106482