Work

Study on the pathogenicity of Clostridium perfringens alpha toxin

Year: 2025

Type: article

Abstract: toxin and ε toxin were individually cloned and expressed. Simultaneously, recombinant protein immunization experiments and animal challenge experiments were conducted. The significant role of alpha toxin in the pathogenicity of various types of Clostridium perfringens has been established, providing mechanistic insight into α toxin function and the development of genetic engineering subunit vaccines in the future.

Source: Infection Genetics and Evolution

DOI: 10.1016/j.meegid.2025.105811

Authors: Chongli Xu, Yuhan She, Hongli Li, Ling Hou, Wenqiao Ding

Institutions: Chongqing Medical and Pharmaceutical College, Ningxia Medical University, Jilin University of Chemical Technology

Language: English

Topic: Clostridium difficile and Clostridium perfringens research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,730