Work

Prediction of Bronchopulmonary Dysplasia by Diaphragmatic Ultrasound in Preterm Infants: A Prospective Pilot Study

Year: 2025

Type: article

Abstract: BACKGROUND: Diaphragmatic ultrasound showed significant differences between patients with established bronchopulmonary dysplasia (BPD) and healthy controls. The aim of this study was to assess whether diaphragmatic ultrasound could predict the development of BPD in preterm infants < 32 weeks of gestational age. METHODS: ), inspiratory and expiratory peak velocities (I-peak and E-peak) and their ratio to body surface area (BSA), and diaphragmatic thickness fraction (DTF) were measured. Logistic regression and ROC curve analyses were performed to evaluate possible role of these variables as predictive factors for BPD and their accuracy for the prediction of BPD. RESULTS: accurately predict BPD with sensitivity of 92% and specificity of 92%, and sensitivity of 99% and specificity of 79%, respectively. CONCLUSIONS: I-peak/BSA and E-peak/BSA are independent risk factors for the development of BPD. They can early and accurately predict the risk for BPD in very preterm infants contributing to targeted treatment of patients at higher risk of BPD.

Source: Pediatric Pulmonology

DOI: 10.1002/ppul.71243

Authors: Chiara Poggi, Monica Fusco, Giovanni Sassudelli, Iuri Corsini, Carlo Dani

Institutions: Azienda Ospedaliero-Universitaria Careggi, University of Florence

Language: English

Topic: Neonatal Respiratory Health Research

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W4413106526

FWCI: 0.589

Cites: 33

Cited by: 1

Related to: 10