Work

Inhibition of tenascin C rescues abnormally reduced Na currents in dystrophin-deficient ventricular cardiomyocytes

Year: 2025

Type: article

Abstract: Dystrophin deficiency in cardiomyocytes leads to abnormally reduced Na currents. These can be rescued by inhibition of the expression of tenascin C.

Source: American Journal of Physiology-Heart and Circulatory Physiology

DOI: 10.1152/ajpheart.00307.2025

Authors: Jessica Marksteiner, Jakob Sauer, Martin Hohenegger, Faith-Oluwakemi David, Natalie Schindler, Petra Lujza Szabó, Attila Kiss, Christopher Dostal, Bruno K. Podesser, Elena Lilliu, Benjamin Hackl, Hannes Todt, Xaver Koenig, Karlheinz Hilber, Klaus Schicker

Institutions: Medical University of Vienna, Ludwig Boltzmann Institute for Cardiovascular Research

Language: English

Topic: Cardiac electrophysiology and arrhythmias

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: Austrian Science Fund, Ludwig Boltzmann Gesellschaft

Awards: G1550908954, G2486794629, G3334548386

OpenAlex ID: W4413106606

FWCI: 0.649

Cites: 44

Cited by: 1

Related to: 10