Effects of a single application of hydrolyzed fish collagen on dermal protein expression and tissue architecture in human skin models
Year: 2025
Type: article
Abstract: The use of collagen as an active ingredient in cosmetic products is becoming increasingly common. Recently, scientific interest has been focused on fish collagen, which is similar to human collagen and can be extracted from fish by-products. This study evaluates the cosmetic potential of Hydrolyzed Fish Collagen (HFC), testing it both as an aqueous solution (S-HFC) and as a formulation in cosmetic products (F-HFC) containing the same amount of HFC. The effects of S-HFC and F-HFC were evaluated on 2D (endothelial and keratinocyte cells) and 3D (EpiDerm and EpiDerm-FT) skin models. The results demonstrated that HFC, as an active ingredient, shows promising effects on skin physiology, including increased cell viability, enhanced wound healing, and an anti-wrinkle effect.
Source: Scientific Reports
Institutions: University of Pisa, University of Genoa
Language: English
Subfield: Biomaterials
Field: Materials Science
Domain: Physical Sciences
Open Access status: gold
Estimated APC paid: $2,690
OpenAlex ID: W4413107334