Work

Synthesis and Preclinical Evaluation of Druglike 18F-Labeled Fibroblast Activation Protein (FAP) Inhibitors with Enhanced Tumor Retention

Year: 2025

Type: article

Source: Bioconjugate Chemistry

DOI: 10.1021/acs.bioconjchem.5c00366

Authors: Karuna Adhikari, Sergei Grintsevich, Anke de Groot, Emile Verhulst, Yentl van Rymenant, Christel Vangestel, Louis Lauwerys, Alan Miranda, Ingrid De Meester, Pieter Van der Veken, Filipe Elvas

Institution: University of Antwerp

Language: English

Topic: Radiopharmaceutical Chemistry and Applications

Subfield: Radiology, Nuclear Medicine and Imaging

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Fonds Wetenschappelijk Onderzoek, Universiteit Gent, Bijzonder Onderzoeksfonds UGent

Awards: Cell-type specific delivery of autophagy inducers as a strategy to address localized autophagy impairment in disease, G5719363342, G6558604759, G829022315, Druglike FAPIs with maximal target residence time: from chemical discovery to preclinical evaluation in oncology and fibrosis theranostics., G966996206

OpenAlex ID: W4413107845

FWCI: 2.639

Cites: 50

Cited by: 5

Related to: 10