Work

Giant atypical meningioma diagnosis and clinical treatment: a case report

Year: 2025

Type: article

Abstract: Giant atypical meningioma (WHO grade 2), predominantly female-associated and rare in males. A 23-year-old male presented with episodic limb paralysis and progressive vision/olfaction decline. Magnetic resonance imaging (MRI) revealed a > 8 cm heterogeneously enhancing tumor invading the diploic space with multi-site compression. Preoperative embolization followed by subtotal resection and adjuvant gamma knife radiosurgery achieved 3-year recurrence-free survival. This case highlights: (i) exceptional rarity of young male onset, challenging epidemiological patterns and (ii) the combined strategy of embolization, subtotal resection, and radiotherapy may overcome traditional high recurrence rates in atypical meningiomas, offering insights for individualized management.

Source: Journal of Surgical Case Reports

DOI: 10.1093/jscr/rjaf560

Authors: YanSong Song, ChengLong Zeng, JingKun Yang, Tao Song

Institutions: Shandong Provincial Hospital, Shandong First Medical University

Language: English

Topic: Meningioma and schwannoma management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,000