Work

Myofibroblastoma of the breast in a 5-year-old girl: A case report

Year: 2025

Type: article

Abstract: RATIONALE: Myofibroblastoma is a rare, benign spindle cell tumor originating from the breast stroma. Although it predominantly affects older men and occasionally postmenopausal women, its occurrence in children is exceedingly rare. PATIENT CONCERNS: A 5-year-old girl presented with a palpable mass on the lateral aspect of her left breast. DIAGNOSES: Serial ultrasound examinations were conducted every 6 months for 1 year because the lesion was initially suspected to be a lipoma or an enlarged lymph node. INTERVENTIONS: Owing to progressive enlargement of the mass to 3 cm, surgical excision was performed. A well-defined yellow-white solid mass located in the subcutaneous layer was completely removed. OUTCOMES: The histopathological and immunohistochemical findings confirmed the diagnosis of a myofibroblastoma. The postoperative course was uneventful, and no recurrence has been reported to date. LESSONS: Although extremely rare, myofibroblastoma should be considered in the differential diagnosis of enlarged breast masses in children. Complete surgical excision is the treatment of choice, and regular follow-up is recommended.

Source: Medicine

DOI: 10.1097/md.0000000000043777

Authors: Youn Joo Jung, Ayoung Kang, Miri Ryu, Soo-Hong Kim, Joon Young Park

Institutions: Pusan National University Yangsan Hospital, Pusan National University, Pusan National University Children's Hospital

Language: English

Topic: Breast Lesions and Carcinomas

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,950