Prognostic Value of Lactate/Albumin Ratio and NEWS-Lactate in Predicting Sepsis-Associated Acute Kidney Injury: A Retrospective Analysis.
Year: 2025
Type: article
Study design: Observational Study
Abstract: Introduction: Sepsis-associated acute kidney injury (SA-AKI) is a frequent complication in critically ill patients and is associated with increased mortality. This study aimed to evaluate the prognostic value of the lactate/albumin ratio (LAR) and other albumin-based biomarkers in predicting SA-AKI. Methods: A retrospective observational study was conducted on 564 patients with sepsis, divided into two groups based on the presence (n = 298) or absence (n = 266) of AKI. Clinical characteristics, laboratory parameters, and disease severity scores (SOFA, APACHE II, NEWS, NEWS-Lactate) were compared between groups. The predictive performance of each marker in detecting SA-AKI was assessed using receiver operating characteristic (ROC) curve analysis. Results: procalcitonin (PCT) Conclusion: for early detection of SA-AKI and may outperform conventional severity scores and standalone laboratory parameters.
Source: PubMed
Authors: Duong Le Xuan, Ghi Nguyen Hai, Duc Vu Anh, Hoa Do Thanh
Institution: 108 Military Central Hospital
Language: English
Topic: Acute Kidney Injury Research
Subfield: Nephrology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W4413113977