Human-Focused Multiparameter Optimization Scores for Rank Ordering Compounds during Early Drug Discovery: Validation of PBPK Models Based on Clinical PK Data
Year: 2025
Type: article
Source: Journal of Medicinal Chemistry
Authors: Yanran Wang, Wenyi Wang, Fabio Broccatelli, Jane R. Kenny, Matthew R. Wright, Jon Sorenson, Prashant Desai
Institutions: Genentech, Gouvernance, Risque, Environnement, Développement
Language: English
Subfield: Computational Theory and Mathematics
Field: Computer Science
Domain: Physical Sciences
Open Access status: closed
Funder: Genentech
OpenAlex ID: W4413115372