Year: 2025
Type: article
Abstract: While perhaps best known for its role in the semiconductor device industry, silicon at the nanoscale is drawing extensive attention to biotech applications such as drug delivery as a consequence of structural diversity and biomedically useful properties. In this focused review we specifically center on one-dimensional nanotubes of silicon by first discussing fabrication routes and then cover fundamental studies of silicon-based nanotube structures relevant to applications in non-traditional platinate chemotherapy as well as gene therapy. Two types of basic platforms are described: (1) freestanding nanotube bundles as well as (2) patterned arrays. Our emphasis here is with regard to tunability of structure tailored to a given application. We conclude with a discussion of existing challenges and opportunities for the future.
Source: Nanomedicine
Authors: Nguyen T. Le, Jeffery L. Coffer
Institution: Texas Christian University
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
Funder: Welch Foundation
Award: G1846993793
OpenAlex ID: W4413116607