A Case of Epithelialization Achieved with Application of Perifascial Areolar Tissue (PAT) Grafting and EPIFIX for the Treatment of Diabetic Foot Ulcer with an Exposed Tendon
Year: 2025
Type: article
Study design: Case Report
Abstract: The treatment of diabetic foot ulcers involving exposed tendons and bones poses significant challenges owing to insufficient blood supply to these surfaces, which limits the applicability of dehydrated human amnion/chorion membrane allografts (EPIFIX).The successful epithelialization of a dorsal diabetic foot ulcer exposing the extensor tendon by combining perifascial areolar tissue grafting with EPIFIX application in a 61-year-old man is described.Perifascial areolar tissue grafting was performed on the tendon, and two weeks later, EPIFIX was applied weekly for 12 weeks as the granulation tissue developed.Complete epithelialization of the wound was observed.The patient subsequently expressed satisfaction with both the functional and cosmetic outcomes.
Authors: Azusa Yoshioka, Noriko Saegusa, Atsutoshi Sato
Institution: Tokyo Metropolitan Bokutoh Hospital
Language: English
Subfield: Endocrinology, Diabetes and Metabolism
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413122200
