Year: 2025
Type: article
Abstract: This review highlights tumor electrophysiological hallmarks as therapeutic targets in precision oncology. We examine how membrane potential alterations and ion channel fingerprints drive malignancy, and how targeted intervention—including channel-specific drugs, electric field therapies, and nanodrug delivery systems—can disrupt these processes, particularly when combined with immunomodulation to enhance antitumor responses and overcome treatment resistance.
Source: iMetaMed
DOI: 10.1002/imm3.70002
Authors: Kailai Li, Yasi Zhang, Yue Qian, Hu Qin, Hongtian Zhang, Chaoqun Li, Changmin Peng, Jian Zhang, Suyin Feng
Institutions: Zhujiang Hospital, Southern Medical University, Xinjiang Medical University, First Affiliated Hospital of Xinjiang Medical University, Chinese PLA General Hospital, UPMC Hillman Cancer Center, University of Pittsburgh Medical Center, George Washington University, Kangda College of Nanjing Medical University
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W4413128506