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Role of microRNA in assessing cardiovascular risk in patients with familial hypercholesterolemia

Year: 2025

Type: article

Abstract: The most common inherited form of dyslipidemia and the main cause of premature cardiovascular disease is familial hypercholesterolemia. This disease is characterized by high levels of low-density lipoprotein cholesterol and, as a consequence, early coronary atherosclerosis and coronary artery disease. Modern research increasingly focuses on the role of small non-coding ribonucleic acids (RNA), in particular microRNA, in the regulation of lipid metabolism and the development of atherosclerotic changes. The aim of this review was to analyze recently published studies describing the potential role of microRNA in assessing cardiovascular risk in patients with familial hypercholesterolemia.

Source: CARDIOVASCULAR THERAPY AND PREVENTION

DOI: 10.15829/1728-8800-2025-4448

Authors: V. I. Mikhailina, A. V. Kiseleva, V. A. Kutsenko, A. N. Meshkov, O. M. Drapkina

Institution: National Medical Research Center of Cardiology

Language: English

Topic: MicroRNA in disease regulation

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413129397

FWCI:

Cites: 29

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Related to: 10