Work

Droplet-based cell viability assay for analysis of spheroid formation, proliferation and high-resolution IC 50 profiling

Year: 2025

Type: article

Abstract: Establishment of a cell viability assay for 3D cell cultures in the droplet-based pipe based bioreactors ( pbb ) platform. The pbb technology enables the determination of high-resolution IC 50 values and proves to be a useful tool for disease modelling.

Source: Lab on a Chip

DOI: 10.1039/d5lc00495k

Authors: Mario Saupe, Stefan Wiedemeier, Franziska Moll, J. Michael Köhler, Doris Heinrich, Karen Lemke

Institutions: Technische Universität Ilmenau, Institute for Bioprocessing and Analytical Measurement Techniques

Language: English

Topic: 3D Printing in Biomedical Research

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Thüringer Ministerium für Wirtschaft, Wissenschaft und Digitale Gesellschaft