Work

In situ synthesis and characterization of polycarbazole–copper oxide (PCz–CuO) nanocomposite: investigating superior antibacterial performance and FabI/FabH docking interactions

Year: 2025

Type: article

Abstract: , respectively) compared to PCz (3.4-14.5 mm and 3.5-15.2 mm). Docking simulations provided insights into possible binding interactions between the synthesized materials and the target enzymes. The results are consistent with a potential for inhibitory activity, which may help explain the observed differences in antibacterial behavior. Overall, this study demonstrates the potential of PCz-CuO as an antibacterial agent and highlights the complementary role of molecular docking in guiding further mechanistic studies.

Source: RSC Advances

DOI: 10.1039/d5ra02065d

Authors: Jahangir Ahmad War, Qurat Ul AIn, Mohammed Iqbal Zargar, Hamida-Tun-Nisa Chisti

Institutions: National Institute of Technology Srinagar, University of Kashmir

Language: English

Topic: Antimicrobial agents and applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,042