Work

Cascade-activatable NIR-II fluorescent carbonic anhydrase inhibitors for imaging-guided cuproptosis/chemodynamic combination therapy of colorectal cancer

Year: 2025

Type: article

Abstract: This work reports a cascade-activatable NIR-II fluorescent inhibitor for colorectal cancer therapy. Its fluorescence signal can be sequentially activated, and it can conduct cuproptosis and chemodynamic therapy.

Source: Chemical Science

DOI: 10.1039/d5sc04668h

Authors: Pu Xu, Yuxin Huang, Gaoyuan Liu, Xuxuan Gu, Xupeng Sun, Yingna Bi, Wen Zhou, Chen Xie, Quli Fan

Institutions: Nanjing University of Posts and Telecommunications, Qilu Normal University

Language: English

Topic: Nanoplatforms for cancer theranostics

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funders: Synergetic Innovation Center for Organic Electronics and Information Displays, National Natural Science Foundation of China, Government of Jiangsu Province, Natural Science Foundation of Jiangsu Province, Nanjing University of Posts and Telecommunications, Nanjing University, Basic Research Program of Jiangsu Province

Awards: G1495424930, G1665678741, G2166675615, G4105207728, G519254759, G5277166330, G79713105, G8317533372

OpenAlex ID: W4413176370

FWCI: 1.927

Cites: 49

Cited by: 8

Related to: 10