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Comparitive Evaluation Of The Pain Relieving Effects Of Pregabalin And Methylcobalamin Alone Or In Combination With Nortriptyline In Neuropathic Pain Management: A Prospective Study

Year: 2025

Type: article

Abstract: This study compared the pain relief of two treatment regimens for neuropathic pain: Pregabalin and Methylcobalamin [PM] versus Pregabalin, Methylcobalamin and Nortriptyline [PMN]. In this prospective observational study, 96 patients received either PM or PMN over 6 months. Both groups showed significant pain reduction, but PMN provided more sustained pain relief, albeit with increased adverse effects like sedation and drowsiness. The study concludes that PMN offers more sustained pain relief, highlighting the need for careful consideration of treatment options.

Source: African Journal of Biomedical Research

DOI: 10.53555/j5nd9a93

Authors: Astha Mercy Kunjumon, Gayathri MM, Fathima Silara Av, Nadha Mansoor, Shameema Thasni C, Ms. Sareena A, Dr. Nithin Br

Institution: KMCT Group of Educational Institutions

Language: English

Topic: Pain Mechanisms and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413177409

FWCI:

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