Year: 2025
Type: article
Study design: Observational Study
Abstract: Objectives To examine fatigue levels in individuals with late-life depression (LLD) and to identify which specific factors significantly affect fatigue severity in these individuals. Methods We included 91 adults (51 LLD and 40 nondepressed individuals), 60% femeles, age range between 60 and 85 yeas. Diagnosis of major depressive episode was defined by the DSM-5 diagnostic criteria and fatigue severity was evaluated by the Fatigue Assessment Scale. Results Individuals with LLD showed significantly higher total scores on the FAS (t 90 =11.81, p=0.002). Fatigue severity was signifcanlty predicted by MADRS (t 82 = 2.74, p=0.07), PSS (t 82 = −4.21, p <0.001), and WHODAS scores (t 82 = 5.23, p <0.001). Conclusion Fatigue is common and disabling symptom associated with LLD. Interventions that promote reduction in fatigue levels can have a significant impact on disability and quality of life of individuals with LLD.
Authors: Amanda Sce, Breno S. Diniz
Institution: UConn Health
Language: English
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
Estimated APC paid: $2,700
OpenAlex ID: W4413177702