Work

Development and evaluation of N -acetyl cysteine-grafted polyamidoamine dendrimers for enhanced brain delivery of donepezil hydrochloride

Year: 2025

Type: article

Abstract: N -acetyl cysteine-conjugated PAMAM G4 dendrimers for brain-targeted delivery of donepezil. The developed system showed high loading, sustained release, improved cell viability, and enhanced pharmacokinetics for Alzheimer’s therapy.

Source: RSC Pharmaceutics

DOI: 10.1039/d5pm00119f

Authors: Teeja Suthar, Keerti Jain

Institutions: National Institute of Pharmaceutical Education and Research, National Institute of Pharmaceutical Education and Research

Language: English

Topic: Dendrimers and Hyperbranched Polymers

Subfield: Polymers and Plastics

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: diamond

Funder: National Institute of Pharmaceutical Education and Research, Raebareli

OpenAlex ID: W4413178601

FWCI: 1.401

Cites: 33

Cited by: 6

Related to: 10