Work

Presacral tumors: a retrospective analysis of 112 cases with emphasis on diagnostic challenges and surgical outcomes

Year: 2025

Type: article

Abstract: Background: Presacral tumors are rare entities with heterogeneous pathology including malignant potential. Due to nonspecific symptoms mimicking common anorectal diseases, misdiagnosis remains a major challenge that may delay treatment and worsen prognosis, particularly for malignant variants. This study analyzes diagnostic pitfalls and surgical outcomes in a large single-center cohort. Methods: We retrospectively reviewed 112 presacral tumor cases treated at our tertiary colorectal center (2015-2025). Data included demographics, clinical presentation, misdiagnosis rates, imaging accuracy, surgical approaches, and complications. Statistical analysis utilized descriptive methods and Chi-square tests. Results: = 5/112), including hemorrhage, rectal injury, and sacral nerve injury. No mortality occurred. Pathology revealed 11.6% malignancy risk. Conclusion: High misdiagnosis rates (29.5%) data support for heightened suspicion in patients with "refractory perianal sepsis", especially given the potential for malignancy. MRI showed significantly higher diagnostic accuracy for tumors >3 cm. Transsacral/transanal resection is safe and effective for most cases (93.8%), with low major morbidity. Centralized management in specialized centers optimizes outcomes.

Source: Frontiers in Surgery

DOI: 10.3389/fsurg.2025.1638820

Authors: Shi Chen, Heng Deng, Ming Li, Xiaoli Fang

Institution: Anhui University of Traditional Chinese Medicine

Language: English

Topic: Colorectal and Anal Carcinomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801