Correlation between baseline magnetic resonance imaging features and serum carcinoembryonic antigen levels in patients with primary rectal cancer
Year: 2025
Type: article
Study design: Observational Study
Abstract: BACKGROUND: Serum carcinoembryonic antigen (CEA) levels and magnetic resonance imaging (MRI) findings are widely used for the diagnosis and treatment of rectal cancer; however, research investigating their correlation remains limited. AIM: To investigate the correlation between baseline MRI features and serum CEA levels in patients diagnosed with primary rectal cancer. METHODS: Eighty patients (age: 42-78 years) diagnosed with primary rectal cancer were enrolled. Baseline MRI examinations were performed to evaluate tumor size, T stage, circumferential resection margin status, extramural vascular invasion (EMVI), and lymph node metastasis. Serum CEA levels were concurrently measured. Statistical methods were used to analyze correlations. RESULTS: < 0.05). Multivariate analysis identified T stage and lymph node metastasis as independent factors influencing serum CEA levels. CONCLUSION: This study confirmed the correlation between baseline MRI features and serum CEA levels in patients with primary rectal cancer, highlighting their potential utility for precise diagnosis, staging, and prognostic evaluation.
Authors: Peng Wang, Wen-Na Zhao, Jun Han, Kai-Xuan Wang, Xiao-Feng Yang, Yi-Juan Huang
Institutions: Jiaxing University, First Hospital of Jiaxing
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413183072