Work

Investigation of 6,7,8-trimethyllumazine and its radicals by NMR and photo-CIDNP spectroscopy

Year: 2025

Type: article

Abstract: radical, the latter potentially protonated at N1. Comparative analysis reveals a substantially different hyperfine structure of the formed radical species which is rationalized based on calculations of spin density distributions. The results provide important insights into photo-induced one-electron transfer reactions of 6,7-dimethyllumazines and their potential role in redox processes in biological systems. The detection and characterization of the oxidized TML˙ radical is of special interest as this oxidation state has not been satisfactorily described in the literature so far. Thus this contribution advances the understanding of the mechanism of formation and the structure of lumazine radicals.

Source: Physical Chemistry Chemical Physics

DOI: 10.1039/d5cp02105g

Authors: Sabrina Panter, Boris Illarionov, Jing Chen, Adelbert Bacher, Markus Fischer, Stefan Weber

Institutions: University of Freiburg, Universität Hamburg, Technical University of Munich

Language: English

Topic: Electron Spin Resonance Studies

Subfield: Biophysics

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Funder: Deutsche Forschungsgemeinschaft

Awards: G3319926350, Synthese und spektroskopische Untersuchungen von 5DeazaflavinIsotopologen in isotropen und anisotropen Umgebungen