Year: 2025
Type: article
Abstract: Cancer remains a global health challenge, necessitating the development of novel therapies with improved efficacy and reduced toxicity. Snake venom, a complex mixture of bioactive proteins, peptides, and enzymes, has emerged as a promising source of anticancer agents. These venom-derived components demonstrate diverse anticancer activities, including induction of apoptosis, inhibition of angiogenesis and metastasis, selective cytotoxicity against tumor cells, and immune modulation. Notably, compounds like crotoxin and disintegrins have shown significant preclinical and clinical potential. However, challenges such as toxicity, production scalability, and standardization must be addressed to translate venom-based therapies into clinical use. This review highlights the therapeutic potential of snake venom components in cancer treatment and outlines the mechanisms underlying their anticancer effects.
Authors: R.Asha R.Asha, B.Dinesh B.Dinesh, Dr.S.Swarnalatha Dr.S.Swarnalatha, Dr.J.Karthi Dr.J.Karthi
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W4413194016