Eosinophilic Esophagitis Secondary to Sublingual Immunotherapy Using the Aeroallergen Timothy Grass Pollen Allergy Extract: A Case Report
Year: 2025
Type: article
Study design: Case Report
Abstract: Eosinophilic esophagitis results in a chronic immune-mediated condition of the esophagus characterized by esophageal dysfunction and eosinophil-predominant inflammation. While food-based oral immunity therapy (OIT) is a recognized trigger for eosinophilic esophagitis, the impact of sublingual immunotherapy (SLIT) for aeroallergens is less well established. We present an unusual case of eosinophilic esophagitis in a 14-year-old male induced by SLIT and resolved after discontinuing SLIT with Timothy grass pollen allergy extract (GRASTEK®, ALK-Abelló, Inc., Bedminster, USA), which, to our knowledge, has not been previously reported.
Source: Cureus
DOI: 10.7759/cureus.89867
Authors: Ashwin Agrawal, Jonathan E Teitelbaum, Wendy Shertz-Dipietro, Petro Vavrukh
Institution: Monmouth Medical Center
Language: English
Topic: Eosinophilic Esophagitis
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413195591