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Extragnathic Giant Cell Granuloma as a Rare Consideration for a Periorbital Mass in an Infant: A Case Report

Year: 2025

Type: article

Abstract: Giant cell granulomas (GCGs) are a benign condition that commonly affects females in their first and second decades of life and almost exclusively involves the jaws. We describe a rare presentation of a GCG involving the zygomatic bone in a five-month-old infant, an exceedingly uncommon location and age group for this entity. While GCGs are most frequently seen in the mandible or maxilla of young females, to our knowledge, there are no previous reports describing zygomatic involvement in this age group. Through detailed multimodality imaging, surgical pathology, and clinical follow-up, we highlight the diagnostic considerations, recurrence potential, and role of adjuvant therapy in managing this lesion.

Source: Cureus

DOI: 10.7759/cureus.89820

Authors: Gabriela N Cepeda De Jesus, Ernest F Hidalgo Cedeno, Ajay Malhotra

Institutions: Hartford Hospital, Yale University

Language: English

Topic: Oral and Maxillofacial Pathology

Subfield: Oral Surgery

Field: Dentistry

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413213433