Work

Respiratory Involvement During the Course of Hypocomplementemic Urticarial Vasculitis: A Case Report

Year: 2025

Type: article

Abstract: Hypocomplementemic urticarial vasculitis syndrome is a rare small-vessel vasculitis characterized by the combination of vasculitis and chronic urticaria. The hypocomplementemic form is distinguished by a more severe clinical presentation than the normocomplementemic form, with prognosis influenced by respiratory involvement. Due to its rarity and the similarities in presentation to systemic lupus erythematosus (SLE), diagnosis may be delayed and treatment may be inappropriate. We report the case of a young non-smoking female patient with a history of SLE refractory to standard treatments, whose progression was marked by severe and irreversible obstructive ventilatory disorder. This case aims to highlight the potential for severe and irreversible obstructive disorders that may occur in this condition in young non-smoking patients.

Source: Cureus

DOI: 10.7759/cureus.89813

Authors: Leroy Dorian, Rudi Peché, Julien Guiot, Sebastien Van Laethem

Institutions: Université Libre de Bruxelles, University of Liège, Centre Hospitalier Universitaire de Liège

Language: English

Topic: Vasculitis and related conditions

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413213644