Work

An Ingeniously Designed Skin Lesion Classification Model Across Clinical and Dermatoscopic Datasets

Year: 2025

Type: article

Abstract: Background: Skin cancer diagnosis faces critical challenges due to the visual similarity of lesions and dataset limitations. Methods: This study introduces HybridSkinFormer, a robust deep learning model designed to classify skin lesions from both clinical and dermatoscopic images. The model employs a two-stage architecture: a multi-layer ConvNet for local feature extraction and a residual-learnable multi-head attention module for global context fusion. A novel activation function (StarPRelu) and Enhanced Focal Loss (EFLoss) address neuron death and class imbalance, respectively. Results: Evaluated on a hybrid dataset (37,483 images across nine classes), HybridSkinFormer achieved state-of-the-art performance with an overall accuracy of 94.2%, a macro precision of 91.1%, and a macro recall of 91.0%, outperforming nine CNN and ViT baselines. Conclusions: Its ability to handle multi-modality data and mitigate imbalance highlights its clinical utility for early cancer detection in resource-constrained settings.

Source: Diagnostics

DOI: 10.3390/diagnostics15162011

Authors: Ying Huang, Zhishuo Zhang, Xin Ran, Kaiwen Zhuang, Yuping Ran

Institutions: Sichuan University, West China Hospital of Sichuan University, University of Electronic Science and Technology of China

Language: English

Topic: Cutaneous Melanoma Detection and Management

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,137