Work

Detection of Drug-Related Problems Associated with High-Risk Medications in a Clinical Setting – A Prospective Study

Year: 2025

Type: article

Abstract: Background: Drug-Related Problems (DRPs) associated with High-Risk Medications (HRMs) present significant challenges in clinical practice, particularly among older adults with multiple comorbidities. This study aimed to identify, classify, and address DRPs in patients prescribed HRMs at a tertiary care hospital in Kerala. Methods: A prospective interventional study was conducted over ten months, enrolling 201 patients aged 18 years and above, of whom 193 completed the protocol. Prescriptions involving HRMs from the cardiology, neurology, general medicine, and psychiatry departments were reviewed using the APS-Doc framework to classify DRPs. Pharmacist-led interventions were implemented to resolve identified issues, including dosage adjustments, drug substitutions, and enhanced patient monitoring.

Source: International Journal of Advancement in Life Sciences Research

DOI: 10.31632/ijalsr.2025.v08i03.015

Authors: Ameena Kadar K A, Sreeja P A, Soumya P V, Dawn V J, Surabhi Mohan K, Irene V R

Institutions: Kerala University of Health Sciences, Dr. M.G.R. Educational and Research Institute

Language: English

Topic: Pharmaceutical Practices and Patient Outcomes

Subfield: Geriatrics and Gerontology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W4413225501