Work

Selective Mono- and Diamination of 2,6-Dibromopyridine for the Synthesis of Diaminated Proligands

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Selective mono- or diaminations of 2,6-dibromopyridine were performed using microwave irradiation with water as solvent in 2–2.5 h. The only significant difference between the syntheses was the inclusion of K 2 CO 3 as base and CuI/DMPAO catalyst for the diaminations. The mono- and diaminations had approximately 7 and 2 g isolated yields, respectively. The monoaminated bromopyridines were attached to a TREN scaffolding molecule yielding novel ligands to support extended metal atom chain complexes.

Source: ACS Omega

DOI: 10.1021/acsomega.5c04396

Authors: Alexander S. Underwood, Mark A. Botrous, Nate T. Lobb, Emmett M. Neal, Charlotte A. Richter, Mathieu A. Sleiman, Adrian B. Frye, Matthew Roberts, Clifford W. Padgett, Gary L. Guillet

Institutions: Furman University, Georgia Southern University

Language: English

Topic: Microwave-Assisted Synthesis and Applications

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,935

Funders: National Science Foundation, Georgia Southern University, Furman University, Division of Chemistry

Awards: RUI: Extended Metal Atom Chain Complexes of Fe and Co Supported by a C3 Symmetric, Scaffolded Ligand Platform, G2902789093, MRI: Acquisition of a Single-Crystal X-ray Diffractometer for Interdisciplinary Research and Enhanced Student Training Supporting Primarily Undergraduate Institutions in Georgia

OpenAlex ID: W4413227181

FWCI:

Cites: 38

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Related to: 10