Work

Expanding the silyl-Prins toolbox: selective access to C4-quaternary stereocenters in tetrahydropyrans using internal cyclopropylsilyl alcohols

Year: 2025

Type: article

Abstract: The use of internal cyclopropylsilyl alcohols in Prins cyclization is reported as a methodology for the stereoselective construction of tetrahydropyrans bearing a quaternary stereocenter.

Source: Organic Chemistry Frontiers

DOI: 10.1039/d5qo00984g

Authors: Paula González-Andrés, Alberto Cherubin, Asunción Barbero

Institution: Universidad de Valladolid

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: Ministerio de Ciencia, Innovación y Universidades

Awards: G1445818959, G3977170102

OpenAlex ID: W4413228542

FWCI: 0.298

Cites: 28

Cited by: 1

Related to: 10