Work

Replacing fishmeal with composite plant protein meal affects nutrient metabolism via mTOR signaling pathway of Pacific white shrimp (Litopenaeus vannamei)

Year: 2025

Type: article

Abstract: < 0.05). It also suppressed the protein synthesis pathway, the mechanistic target of rapamycin (mTOR) pathway, and activated the general control non-derepressible 2 (GCN2) pathway, which detects uncharged tRNA and inhibits protein synthesis. The AMP-activated protein kinase (AMPK) pathway was activated indicating energy deprivation in response to dietary plant protein. In summary, high levels of dietary plant protein inhibited the mTOR signaling pathway, activated the GCN2 and AMPK signaling pathways, and promoted lipid deposition in the hepatopancreas. These findings provide insights into the molecular mechanisms underlying phenotypic changes in shrimp fed different protein sources.

Source: Animal nutrition

DOI: 10.1016/j.aninu.2025.04.014

Authors: Ranran Zhao, Xuan Wang, Huihui Zhou, Chengdong Liu, Kangsen Mai, Gen He

Institution: Ocean University of China

Language: English

Topic: Aquaculture Nutrition and Growth

Subfield: Aquatic Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: gold

Estimated APC paid: $1,462