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Luminescent Zn2GeO4:Mn2+ Nanoparticles with High Quantum Yield for Salivary Protein Detection

Year: 2025

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Zinc germanate doped with Mn 2+ (Zn 2 GeO 4:Mn 2+ ) is known to be a green luminescence phosphor with many applications in biosensing and bioimaging. This study presents a simple method for creating small size Zn 2 GeO 4:Mn 2+ nanoparticles using a combination of the coprecipitation–molten salt synthesis method. These nanoparticles exhibit bright green luminescence under UV excitation. After surface functionalization, these nanoparticles were then used to develop a fluorescence resonance energy transfer (FRET)-based immunoassay. This immunoassay shows a detection range of 5–20 ng/mL of C-reactive protein (CRP), which suggests its potential for simple solution CRP detection and broader applications in protein biosensing.

Source: ACS Applied Nano Materials

DOI: 10.1021/acsanm.5c02725

Authors: Yuchen Zhang, Yuanbing Mao

Institution: Illinois Institute of Technology

Language: English

Topic: Luminescence Properties of Advanced Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: Illinois Institute of Technology, Office of Science, National Institute of Dental and Craniofacial Research