Non-targeted and chiral amino acid metabolomics of colon cancer: Revealing novel chiral biomarkers and metabolic pathways
Year: 2025
Type: article
Abstract: • Non-targeted and DL-amino acid metabolomics employed for biomarker screening in CRC • A novel chiral mass spectrometry probe, TPP-BSA, was developed • Simultaneous separation of 13 chiral amino acids achieved using a C18 column • First-time revelation of the correlation between serum D-amino acids and CRC • Characterization of pathways potentially contributing to the development of CRC
Authors: Yuxuan Li, Xinxin Kong, Guangyi Zhang, Hongzhu Jin, Xi-Ling Li, Toufeng Jin, Jun Zhe Min
Institutions: Yanbian University, Yanbian University Hospital
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: gold
Estimated APC paid: $1,950
OpenAlex ID: W4413234244