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Juvenile Myasthenia Gravis: Musk Positive: with 3 Cardinal signs

Year: 2025
Type: article
Study design: Case Report
Abstract: Anti muscle specific tyrosine kinase (Musk) antibody is the most common antibody identified in seronegative myasthenia gravis (SNMG). Juvenile onset musk myasthenia has different clinical course as demonstrated in our case with spontaneous remission followed by resurgence of symptoms with ocular complaints. Musk myasthenia characteristically presents with bulbar and respiratory muscle involvement with a high rate of myasthenic crisis. Early identification is necessary to decrease the incidence of myasthenic crisis. We report a atypical case of musk myasthenia gravis with 3 cardinal signs which responded completely to immunosuppressants.
Author: Agrata Sharma
Language: English
Subfield: Neurology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W4413236980
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Related to: 10