Year: 2025
Type: article
Study design: Case Report
Abstract: Local anesthetics (LAs) are widely used to relieve surgical pain. Pure amide-type LAs rarely cause allergic reactions. Here, we present a case of anaphylaxis induced by multiple pure amide agents. We report a case of a 17-year-old girl with no history of allergies who was scheduled to undergo orthopedic surgery. She presented with anaphylactic symptoms after receiving peripheral nerve blocks. Postoperative allergy tests were positive for two kinds of amide-type LAs: pure lidocaine and ropivacaine. In conclusion, cross-reactivity should be considered in case of an allergic reaction to an amide-type agent.
Source: Cureus
DOI: 10.7759/cureus.89655
Authors: Hikaru Matsumoto, Akira Nemoto, Yukitoshi Niiyama
Institution: Akita University
Language: English
Subfield: Pharmacology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W4413241483