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Case Report: Successful endoscopic full-thickness resection of an irregular submucosal tumor of the esophagus with surface focal white patches: horseshoe-shaped leiomyoma

Year: 2025

Type: article

Abstract: Esophageal leiomyoma is a rare benign tumor of the esophagus, accounting for approximately 1.2% of all esophageal tumors. Endoscopically, it typically appears as a protrusion into the esophageal lumen with intact and smooth mucosa, which can be slightly moved with biopsy forceps and rarely causes luminal stenosis. The current case presents an irregular submucosal esophageal mass with localized white patches on the surface-an endoscopic appearance not previously reported. These surface white patches complicated the diagnosis, and the postoperative pathological finding of a horseshoe-shaped leiomyoma is even more unusual. Preoperative imaging with chest and abdominal CT and endoscopic ultrasound identified the lesion in the muscularis propria, and successful endoscopic full-thickness resection was performed. This minimally invasive approach was confirmed by pathology to be precise, safe, and effective, achieving treatment outcomes comparable to traditional surgical resection.

Source: Frontiers in Oncology

DOI: 10.3389/fonc.2025.1583882

Authors: Lili Pan, Chuanfang Wang, Chong Zhang, Lijuan Fan, Ran Ma

Institution: Jining First People's Hospital

Language: English

Topic: Gastrointestinal Tumor Research and Treatment

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801