Copper-catalyzed Oxidation C(sp3)–H Difunctionalization of Xanthene Derivatives to Construct Triaryl Tertiary Alcohols
Year: 2025
Type: preprint
Abstract: Under aerobic copper catalysis, an unprecedented direct selective synthesis of triaryl-substituted tertiary alcohols via single electron oxidation induced coupling of xanthenes, O 2 with aromatic amines is presented. The protocol provides an atom-economic approach to chemoselective C–C, C–O bond formation, proceeding with the merits of broad substrate scope, operational simplicity, good functional group compatibility, and mild reaction conditions
Authors: He Zhao, Qinghao Song, Yaping Zhu, Xinyan Yu, Yanping Sun, Yong Dai, Changjian Zhou
Language: English
Subfield: Organic Chemistry
Field: Chemistry
Domain: Physical Sciences
Open Access status: gold
OpenAlex ID: W4413267121